Fructus Crataegi Extract Lipidity-Lowering Tablets have been put on
the market for a decade and have been used by several mill'ions of domestic and foreign
patients afflicted with angio-cardiopathy. The Angio-cardiopathy Research Institute of
Fujian Province once formed a coordinated group forpreventing and curing angio-cardiopathy
within Fujian Province. The Research Institute of Traditional Chinese Medicine of Fujian
Province administered Fructus Crataegi Extract Lipidity-Lowering Tablets to patients three
times daily,two tablets each time, unifying forms, treatment plans, observation results
and evaluation norms so as to carry out clinical tests and verifications. The results are
as follows:
(I) Lipid-Lowering Effect
| ¡¡ |
Pre-treatment |
Post-treatment drop |
P value |
| cholesterol |
208¡«344mg% |
36¡À5.4 |
<0. O1 |
| triglycerido |
125¡«625mg% |
64¡À8.8 |
<0. O1 |
| ¡¡ |
Remarkable (drop>30mg%) |
Total effective rate |
| cholesterol |
48.51% |
84.15% |
| triglycerido |
64.29% |
77.39% |
Comparison (average) with the Control Groups
Conducted by the Angio-cardiopathy Research Institute of Fujian Province.
| ¡¡ |
Fructus Crataegi Extract |
Atromid-s |
Hexanicotol |
| drop of cholesterol |
75.67mg |
73mg |
74.25mg% |
| drop of triglycerido |
65mg |
¡ü6.9mg |
¡ý26.57mg% |
This shows that the effect of Fructus Crataegi
extract is similar to that of Atromid-s or Hexanieotol in lowering cholesterol,but is
superior to that of Atromid-s or Hexanicotol in lowering triglycerido.
(¢ò) Blood Pressure-Lowering Effect
| ¡¡ |
Pre-treatment |
Post-treatment |
Drop |
P value |
| systolic pressure |
146.26¡À22.46 |
133.2¡À16.4 |
13.0¡À15.5 |
<0.01 |
| diastolic pressure |
87.6¡À13.30 |
81.4¡À9.4 |
6.2¡À11.3 |
<0.01 |
This shows that Fructus Crataegi extract is effective
in lowering both systolic pressure and diastolic pressure.
(¢ó) Effect on the Heart Rate
| Pre-treatment heart rate |
Post-treatment heart rate |
P value |
70-120 beats/m
(average 79.2¡À22.1) |
70.3+18. I beats/m
(drop 8, 9¡À9.6) |
<0.01 |
56-70 beats/m
(average 64.0¡À45) |
71.7¡À6.6 beats/m
(increase 8.9¡À9.6) |
<0.01 |
This shows that Fructus Crataegi has a two-way
regulating effect on the heart rate.
(¢ô) Regulating Effect on Blood Rheology
| ¡¡ |
Pre-treatment |
Post-treatment |
Drop |
P value |
1. Specific viscosity
of whole blood
high section
low section |
4.84¡À0.66
7.14¡À1.61 |
4.404¡À0.54
6.66¡À1.39 |
0.44¡À0.53
0.51¡À1.08 |
<0.01
<0.05 |
| 2. Specific viscosity of plasma |
1.734¡À0.11 |
1.66¡À0.12 |
0.07¡À0.14 |
<0.01 |
It has a marked lowering effect on those cases with evidently
increased SR. CV before treatment,and can be applied to those with thrombotic diseases.
(¢õ) Weight-Reducing Effect
It has a marked weight-reducing effect,bringing the weight down by 1 to 5.5 kilos
after being taken for one month.
(¢ö) Effect on blood Sugar and Liver and Kidney Functions
No change took place after treatment ,and no negative side effects appeared. |